Effect of polyunsaturated fatty acids intake on the occurrence of current asthma among children and adolescents exposed to tobacco smoke: NHANES 2007–2018

Table 4 Moderating effect of omega-6 PUFAs on the association of TSE and current asthma

Variables	Crude model**		Model 5		Model 6
Variables	AOR (95% CI)	P	AOR (95% CI)	P	AOR (95% CI)	P
Cotinine	1.66 (1.29–2.12)	< 0.001	1.53 (1.19–1.97)	0.001	1.35 (1.01–1.83)	0.048
Omega-6 PUFAs	1.21 (0.91–1.62)	0.193	1.16 (0.86–1.57)	0.314	1.24 (0.92–1.69)	0.161
Cotinine * Omega-6 PUFAs	0.88 (0.59–1.31)	0.523	0.87 (0.58–1.31)	0.505	0.88 (0.58–1.34)	0.546

AOR adjusted odds ratio, CI confidence interval, Ref reference, PUFAs polyunsaturated fatty acids, TSE tobacco smoke exposure;
Crude Model**: only adjusted serum cotinine, omega-6 PUFAs and serum cotinine*omega-6
Model 5: adjusted serum cotinine, omega-6 PUFAs, serum cotinine*omega-6 PUFAs, age, gender and race
Model 6: adjusted serum cotinine, omega-6 PUFAs, serum cotinine*omega-6 PUFAs, age, gender, race, sedentary time, overweight, relative asthma and hay fever

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