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Table 1 Baseline characteristics of participants in NHANES 2017 to 2020a

From: Association between cardiovascular health and metabolic dysfunction-associated steatotic liver disease: a nationwide cross-sectional study

Characteristic

Nb

Overall CVH

Low CVH

Moderate CVH

High CVH

P value

(n = 5680)

(n = 724)

(n = 3901)

(n = 1055)

Age, mean (SE), y

/

48.03 (0.64)

55.14 (0.93)

49.36 (0.7)

41.02 (0.85)

< 0.001

Age, y

      

 20–39

1767

36.01 (32.95–39.19)

17.17 (12.86–22.56)

32.66 (29.36–36.15)

54.11 (48.99–59.14)

< 0.001

 40–59

1907

34.83 (32.40-37.33)

40.51 (34.34–46.99)

36.37 (33.68–39.13)

27.79 (23.61–32.40)

 ≥ 60

2006

29.16 (25.83–32.73)

42.32 (35.11–49.87)

30.96 (27.19–35.02)

18.10 (14.57–22.27)

Gender

      

 male

2799

49.20 (46.94–51.46)

43.14 (36.93–49.57)

53.84 (50.87–56.79)

38.04 (33.43–42.88)

< 0.001

 Female

2881

50.80 (48.54–53.06)

56.86 (50.43–63.07)

46.16 (43.21–49.13)

61.96 (57.12–66.57)

Race and ethnicity

      

 Hispanic

1259

15.37 (12.63–18.59)

14.39 (11.05–18.52)

15.27 (12.49–18.53)

16.11 (12.63–20.34)

< 0.001

 Non-Hispanic White

2065

65.23 (60.31–69.84)

59.78 (51.52–67.52)

65.71 (60.61–70.47)

66.16 (59.84–71.96)

 Non-Hispanic Black

1432

10.11 (7.73–13.12)

16.77 (12.30-22.44)

10.37 (7.83–13.61)

6.47 (4.94–8.44)

 Othersc

924

9.29 (7.59–11.33)

9.07 (5.88–13.74)

8.66 (7.17–10.42)

11.25 (8.13–15.37)

Poverty income ratio

      

 < 1.3

1344

17.62 (15.82–19.58)

29.03 (22.60-36.43)

17.27 (15.54–19.16)

13.67 (11.44–16.26)

< 0.001

 ≥ 1.3,<3.5

1921

33.51 (30.60-36.55)

43.62 (37.93–49.48)

34.12 (30.69–37.73)

27.34 (23.39–31.67)

 ≥ 3.5

1758

48.87 (45.17–52.59)

27.35(21.22–34.47)

48.60(44.09–53.14)

58.99 (54.55–63.29)

Education levels

      

 High school or less

2262

35.82 (32.58–39.19)

53.98 (50.10–57.80)

38.79(34.63–43.10)

19.17 (16.75–21.85)

< 0.001

 Some college or associates degree

1924

32.55 (29.34–35.93)

32.69 (29.41–36.15)

32.03(30.13–33.99)

25.98 (21.69–30.78)

 College graduate or above

1494

33.46 (29.38–37.80)

13.33 (10.48–16.82)

29.19(24.83–33.96)

54.85 (49.24–60.34)

Marital status

      

 Married/Living with Partner

3356

63.11 (60.13–65.99)

58.14 (50.63–65.29)

64.13 (61.10-67.04)

62.22 (56.71–67.44)

< 0.001

 Widowed/Divorced/Separated

1240

18.10 (16.57–19.73)

27.72 (23.01-33.00)

19.06 (16.81–21.53)

11.08 (8.84–13.81)

 Never married

1084

18.80 (16.59–21.22)

14.14 (10.46–18.39)

16.81 (14.66–19.21)

26.70 (21.64–32.45)

MASLD

      

 yes

2130

36.83 (34.70–39.00)

67.28 (63.03–71.26)

41.47(39.15–43.83)

9.88 (7.35–13.17)

< 0.001

 no

3550

63.17 (61.00-65.30)

32.72 (28.74–36.97)

58.53 (56.17–60.85)

90.12 (86.83–92.65)

Thyroid disease history

      

 yes

675

12.66 (11.47–13.95)

22.19 (14.21–32.93)

11.84 (10.26–13.62)

10.98 (8.92–13.46)

0.003

 no

5005

87.34 (86.05–88.53)

77.81 (67.07–85.79)

88.16 (86.38–89.74)

89.02(86.54–91.08)

Obesity

      

 yes

2427

41.54 (38.46–44.69)

77.39 (71.63–82.28)

47.83 (44.11–51.58)

7.37 (5.60–9.65)

< 0.001

 no

3253

58.46 (55.31–61.54)

22.61 (17.72–28.37)

52.17 (48.42–55.89)

92.63 (90.35–94.40)

Sleep apnea

      

 yes

1356

23.81 (22.29–25.41)

32.00 (26.40-38.17)

24.95 (22.82–27.21)

17.15(13.37–21.74)

< 0.001

 no

4040

76.19 (74.59–77.71)

68.00 (61.83–73.60)

75.05 (72.79–77.18)

82.85 (78.26–86.63)

ALT, mean (SE), U/L

/

22.56 (0.26)

24.30 (0.83)

23.70 (0.34)

18.42 (0.30)

< 0.001

AST, mean (SE), U/L

/

21.44 (0.16)

21.99 (0.64)

21.54 (0.14)

20.91 (0.40)

0.12

GGT, mean (SE), U/L

/

28.28 (0.59)

37.12 (1.88)

30.06 (0.67)

19.18 (0.58)

< 0.001

Poverty income ratio, mean (SE)

/

3.23 (0.06)

2.52 (0.15)

3.22 (0.06)

3.56 (0.07)

< 0.001

LE8 scores (out of 100 possible points)

      

LE8 score, mean (SE)

/

68.25 (0.44)

42.11 (0.33)

65.76 (0.24)

86.95 (0.28)

< 0.001

HEI-2015 diet score, mean (SE)

/

39.02 (1.08)

21.19 (1.15)

35.01 (1.11)

58.65 (1.08)

< 0.001

Physical activity score, mean (SE)

/

76.91 (0.76)

31.07 (3.59)

76.94 (1.16)

96.66 (0.55)

< 0.001

Nicotine exposure score, mean (SE)

/

75.31 (1.00)

46.85 (1.75)

73.38 (1.27)

93.36 (0.88)

< 0.001

Sleep health score, mean (SE)

/

86.24 (0.6)

67.99 (2.26)

86.39 (0.63)

93.69 (0.64)

< 0.001

Body mass index score, mean (SE)

/

57.07 (1.01)

30.66 (1.71)

51.96 (1.21)

83.63 (0.79)

< 0.001

Blood lipids score, mean (SE)

/

67.03 (0.88)

45.11 (1.20)

64.06 (1.29)

85.30 (1.02)

< 0.001

Blood glucose score, mean (SE)

/

76.57 (0.51)

56.13 (1.26)

74.05 (0.69)

92.92 (0.78)

< 0.001

Blood pressure score, mean (SE)

/

67.85 (0.84)

37.88 (1.65)

64.28 (0.84)

91.40 (0.58)

< 0.001

  1. NHANES, National Health and Nutrition Examination Survey; CVH, cardiovascular health; SE, standard error; MASLD, metabolic dysfunction-associated steatotic liver disease; ALT, alanine aminotransferase; AST, aspartate aminotransferase; GGT, gamma-glutamyl transferase; LE8, Life’s Essential 8; HEI, healthy eating index
  2. a Continuous variables are reported as weighted mean (standard error), while categorical variables are reported as weighted percentage with 95% confidence interval
  3. b Numbers of each stratum may not add up to the total population due to missing data
  4. c Others include Non-Hispanic Asian, other non-Hispanic, and multi-race individuals