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Table 2 Association of biological aging and HEI-2015 with risk of NAFLD

From: The effect of healthy eating index-2015 in the associations of biological aging and non-alcoholic fatty liver disease: an interaction and mediation analysis

 

Model 1

 

Model 2

 

Model 3

 
 

OR (95%CI)

P for trend

OR (95%CI)

P for trend

OR (95%CI)

P for trend

Biological aging

 

0.011

 

0.010

 

0.018

Q1 (− 5.700–27.298)

1.00

 

1.00

 

1.00

 

Q2 (27.299–45.723)

1.03 (0.72, 1.48)

 

1.08 (0.74, 1.57)

 

1.24 (0.84, 1.84)

 

Q3 (45.724–61.205)

1.71 (0.98, 2.96)

 

1.83 (1.04, 3.23)*

 

2.07 (1.15, 3.73)*

 

Q4 (61.206–128.515)

2.28 (1.10, 4.74)*

2.42 (1.15, 5.10)*

2.49 (1.16, 5.38)*

HEI-2015

 

0.099

 

0.019

 

0.035

Q1 (6.260–38.384)

1.00

 

1.00

 

1.00

 

Q2 (38.385–47.612)

0.88 (0.64, 1.18)

0.89 (0.66, 1.18)

0.89 (0.66, 1.18)

Q3 (47.613–58.488)

0.80 (0.58, 1.08)

0.86 (0.64, 1.14)

0.87 (0.65, 1.16)

Q4 (58.489–90.905)

0.72 (0.54, 0.96)*

0.61 (0.44, 0.84)**

0.64 (0.46, 0.87)**

  1. Model 1: age and sex. Model 2: model 1 variables plus race/ethnicity, education level, marital status, family poverty income ratio, the complication of hypertension, diabetes mellitus, smoke status, and drink status. Model 3 was adjusted for model 2 variables plus body mass index, waist circumference, fast glucose, high-sensitivity C-reactive protein, alanine aminotransferase, aspartate amino transferase, gamma-glutamyl transpeptidase, uric acid, blood urea nitrogen, serum creatinine, estimated glomerular filtration rate, triglyceride, and high-density lipoprotein-cholesterol
  2. HEI healthy eating index, NAFLD non-alcoholic fatty liver disease, OR odd ratio, CI confidence interval
  3. *P < 0.05; **P < 0.01