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Table 4 Liver function and hepatic steatosis indices assessments of participants based on the groups

From: The effect of chitosan supplementation on liver function, hepatic steatosis predictors, and metabolic indicators in adults with non-alcoholic fatty liver disease: a randomized, double-blinded, placebo-controlled, clinical trial

 

Chitosan (n = 33)

Placebo (n = 33)

P-value

AST (U/l)

 Before

27.36 ± 8.91

26.06 ± 10.58

0.591#

 After

25.09 ± 7.32

26.36 ± 9.11

0.534#

 P-value*

 < 0.001

0.787

 

 Mean differences

− 2.27 ± 3.13

0.30 ± 6.37

0.040†

ALT (U/l)

 Before

37.72 ± 20.35

29.45 ± 19.31

0.095#

 After

33.81 ± 17.61

29.81 ± 19.05

0.379#

 P-value*

 < 0.001

0.656

 

 Mean differences

− 3.90 ± 4.83

0.36 ± 4.64

0.001†

GGT (U/l)

 Before

38.78 ± 31.17

34.72 ± 23.73

0.554#

 After

37.09 ± 29.71

35.03 ± 22.05

0.750#

 P-value*

0.039

0.710

 

 Mean differences

− 1.69 ± 4.51

0.30 ± 4.63

0.028†

TYG

 Before

8.72 ± 0.48

8.77 ± 0.53

0.712#

 After

8.67 ± 0.40

8.82 ± 0.35

0.128#

 P-value*

0.104

0.290

 

 Mean differences

− 0.04 ± 0.16

0.04 ± 0.25

0.159†

HSI

 Before

41.86 ± 5.32

38.33 ± 7.79

0.036#

 After

41.19 ± 4.66

38.11 ± 7.54

0.051#

 P-value*

0.067

0.427

 

 Mean differences

− 0.67 ± 2.03

- 0.22 ± 1.60

0.705†

FLI

 Before

71.16 ± 27.87

58.97 ± 31.40

0.100#

 After

69.69 ± 26.26

59.62 ± 29.58

0.149#

 P-value*

0.134

0.493

 

 Mean differences

− 1.47 ± 5.51

0.65 ± 5.38

0.571†

  1. AST Aspartate Transferase, ALT Alanine Transaminase, GGT Gamma-glutamyl Transferase, TYG Triglyceride Glucose index, HSI Hepatic Steatosis Index, FLI Fatty Liver Index
  2. Mean differences are calculated as: After–Before
  3. Results are shown as mean ± SD
  4. *Paired sample t-test
  5. #Independent sample t-test
  6. †ANCOVA test, adjusted for changes in weight
  7. P-value less than 0.05 considered significant
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Journal of Health, Population and Nutrition

ISSN: 2072-1315

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