Serum indexes | No. of death/Person-years | HR (95% CI) † | ||
---|---|---|---|---|
Model 1 | Model 2 | Model 3 | ||
eGFR (ml/min/1.73m2) | ||||
Q1 (< 70.62) | 1733/31,420 | ref | ref | ref |
Q2 (70.62~) | 1054/34,745 | 0.66 (0.61–0.71) | 0.67 (0.62–0.73) | 0.69 (0.64–0.75) |
Q3 (84.67~) | 865/35,587 | 0.61 (0.56–0.67) | 0.62 (0.57–0.67) | 0.64 (0.59–0.70) |
Q4 (93.07~) | 476/37,173 | 0.51 (0.46–0.57) | 0.52 (0.46–0.58) | 0.53 (0.47–0.59) |
Q5 (≥ 100.34) | 300/37,660 | 0.65 (0.56–0.75) | 0.65 (0.56–0.75) | 0.67 (0.58–0.77) |
P-trend | < 0.001 | < 0.001 | < 0.001 | |
Urea (mmol/L) | ||||
Q1 (< 4.70) | 834/38,695 | ref | ref | ref |
Q2 (4.70~) | 774/37,473 | 0.88 (0.80–0.98) | 0.89 (0.81–0.98) | 0.87 (0.79–0.96) |
Q3 (5.50~) | 689/32,647 | 0.88 (0.80–0.98) | 0.89 (0.81–0.99) | 0.89 (0.81–0.98) |
Q4 (6.20~) | 876/36,109 | 0.93 (0.84–1.02) | 0.95 (0.86–1.04) | 0.91 (0.83–1.01) |
Q5 (≥ 7.30) | 1255/31,662 | 1.35 (1.24–1.48) | 1.36 (1.24–1.48) | 1.27 (1.16–1.39) |
P-trend | < 0.001 | < 0.001 | < 0.001 | |
Uric acid (µmol/L) | ||||
Q1 (< 242.00) | 739/36,151 | ref | ref | ref |
Q2 (242.00~) | 727/36,694 | 0.81 (0.73–0.90) | 0.82 (0.74–0.91) | 0.83 (0.75–0.92) |
Q3 (284.00~) | 786/35,427 | 0.83 (0.75–0.91) | 0.85 (0.77–0.95) | 0.88 (0.79–0.97) |
Q4 (325.00~) | 923/35,049 | 0.88 (0.79–0.97) | 0.91 (0.83–1.01) | 0.93 (0.84–1.03) |
Q5 (≥ 379.00) | 1253/33,264 | 1.11 (1.01–1.22) | 1.17 (1.07–1.29) | 1.21 (1.10–1.34) |
P-trend | < 0.001 | < 0.001 | < 0.001 |