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Table 2 Associations of baseline kidney function indexes with all-cause mortality among participants

From: Associations between kidney function with all-cause and cause-specific mortality in type 2 diabetes mellitus patients: a prospective cohort study in China

Serum indexes

No. of death/Person-years

HR (95% CI)

Model 1

Model 2

Model 3

eGFR (ml/min/1.73m2)

    

Q1 (< 70.62)

1733/31,420

ref

ref

ref

Q2 (70.62~)

1054/34,745

0.66 (0.61–0.71)

0.67 (0.62–0.73)

0.69 (0.64–0.75)

Q3 (84.67~)

865/35,587

0.61 (0.56–0.67)

0.62 (0.57–0.67)

0.64 (0.59–0.70)

Q4 (93.07~)

476/37,173

0.51 (0.46–0.57)

0.52 (0.46–0.58)

0.53 (0.47–0.59)

Q5 (≥ 100.34)

300/37,660

0.65 (0.56–0.75)

0.65 (0.56–0.75)

0.67 (0.58–0.77)

P-trend

 

< 0.001

< 0.001

< 0.001

Urea (mmol/L)

    

Q1 (< 4.70)

834/38,695

ref

ref

ref

Q2 (4.70~)

774/37,473

0.88 (0.80–0.98)

0.89 (0.81–0.98)

0.87 (0.79–0.96)

Q3 (5.50~)

689/32,647

0.88 (0.80–0.98)

0.89 (0.81–0.99)

0.89 (0.81–0.98)

Q4 (6.20~)

876/36,109

0.93 (0.84–1.02)

0.95 (0.86–1.04)

0.91 (0.83–1.01)

Q5 (≥ 7.30)

1255/31,662

1.35 (1.24–1.48)

1.36 (1.24–1.48)

1.27 (1.16–1.39)

P-trend

 

< 0.001

< 0.001

< 0.001

Uric acid (µmol/L)

    

Q1 (< 242.00)

739/36,151

ref

ref

ref

Q2 (242.00~)

727/36,694

0.81 (0.73–0.90)

0.82 (0.74–0.91)

0.83 (0.75–0.92)

Q3 (284.00~)

786/35,427

0.83 (0.75–0.91)

0.85 (0.77–0.95)

0.88 (0.79–0.97)

Q4 (325.00~)

923/35,049

0.88 (0.79–0.97)

0.91 (0.83–1.01)

0.93 (0.84–1.03)

Q5 (≥ 379.00)

1253/33,264

1.11 (1.01–1.22)

1.17 (1.07–1.29)

1.21 (1.10–1.34)

P-trend

 

< 0.001

< 0.001

< 0.001

  1. Abbreviations: HR, hazard ratio; CI, confidential interval
  2. HRs (95% CIs) were calculated by adjusting covariates. Model 1: Adjusted for age and sex. Model 2: Additionally adjusted for education level, annual household income, smoking, alcohol consumption, BMI, WC, physical activity, hypertension, stroke, CHD, cancer, dyslipidemia, kidney diseases, family history of stroke, family history of CHD, family history of diabetes, family history of hypertension and family history of dyslipidemia. Model 3: Additionally adjusted for diabetes duration, oral antidiabetic medication and insulin injection