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Table 2 Demographic characteristics of the included studies

From: The effectiveness of fasting regimens on serum levels of some major weight regulating hormones: a GRADE-assessed systematic review and meta-analysis in randomized controlled trial

Code first author(year)

Location

Study design

Health status

Gender

Sample size

Duration(week)

Range age(year)

Intevention group

Comparator group

Out come

1. Bhutani etal.2013

USA

RCT

Obese

Both

32

12

25–65

ADF

Usual intake

Adiponectin/Leptin

2.Varady et al.2013

USA

RCT

Normal and overweight

Both

30

12

35–50

ADF

Usual intake

Adiponectin/Leptin/Resistin

3.Catenacci etal.2016

USA

RCT

Obese

Both

26

8

18–55

ADF

Energy restricted

Leptin/Ghrelin

4. Moro etal.2016

Italy

RCT

resistance-trained males

Both

34

8

18–20

TRF

Usual intake

Adiponectin/Leptin

5. F. Trepanowskia etal.2018

USA

RCT

Overweight and obese

Male

65

24

18–65

ADF

Usual intake

Adiponectin/Leptin/Resistin

6.T. Stratton etal.2020

USA

RCT

Healthy

Male

26

6

 

TRF

Usual intake

Adiponectin/Leptin/Ghrelin

7.Pureza M.S. etal.2020

Brazil

RCT

Obese

Female

58

3

19–44

TRF

Energy restricted

Leptin

8. Moro etal.2020

Italy

RCT

resistance-trained males

Both

16

4

18–20

TRF

Usual intake

Adiponectin/Leptin

9. Moro etal.2021

Italy

RCT

resistance-trained males

Both

20

12

18–20

TRF

Usual intake

Adiponectin/Leptin

10.Templeman etal.2021

UK

RCT

Healthy

Both

24

3

18–65

ADF

Energy restricted

Adiponectin/Leptin

11. Sadeghian et al.2021

Iran

RCT

Obese

Female

60

8

18–55

FMD

Energy restricted

Leptin/Ghrelin

12.Castela et al.2022

Norway

RCT

obese

Both

28

12

45–59

IF

Energy restricted

Adiponectin/Leptin/Resistin

13.Zhang etal.2022

China

RCT

Obese

Both

30

8

18–30

eTRF

Usual intake

Adiponectin/Leptin

14.Zhang etal.2022

China

RCT

Obese

Both

49

8

18–30

ITRF

Usual intake

Adiponectin/Leptin

15.Çelik et al.2023

Turkey

RCT

Overweight

Female

23

64

19–32

TRF

Energy restricted

Adiponectin/Leptin

16.Czerwi ´ nska-Ledwig etal.2024

Poland

RCT

Obese

Female

25

6

21–85

TRF

Usual intake

Leptin/Resistin

17.Czerwi ´ nska-Ledwig etal.2024

Poland

RCT

Obese

Female

25

8

21–85

TRF

Usual intake

Leptin/Resistin

18.Keawtep et al.2024

Thailand

RCT

Overweight and obese

Female

41

12

45–59

IF

Usual intake

Adiponectin

  1. Abbreviations: USA, United States of America; RCT, Randomized controlled trial; ADF, Alternate Day Fasting; TRF, Time Restricted Feeding; IF, Intermittent Fasting. FMD, fasting mimicking diet