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Table 2 Characteristics of cross-sectional studies included in the systematic review

From: Effect of dietary patterns on functional dyspepsia in adults: a systematic review

First author, Year, Location

Population (Diagnostic criteria)

Number (intervention/control)

Female (%)

Age range/mean age (y)

Dietary pattern

Dietary Measure and analysis

Symptom measure

Ostrowski, 2018, Poland [11]

Healthy volunteer with vegetarian, vegan, or general diet (> 1y)

1209

44.74%

Mean (SD)27.96 (10.74)

Vegetarian diet, Vegan diet

NR (Dichotomized question: “Do you follow a vegetarian or vegan diet?”)

Presence of fullness and bloating by unvalidated questionnaire

Ghoshal, 2017, India [26]

Adult resident of three villages

2,774

1201(43.3%)

38.4 +- 16.5

Vegetarian diet

A questionnaire to obtain data on predominant diet (vegetarian was defined as consuming no food of animal origin except milk)

Presence of dyspepsia by ROME III criteria

Mitsou, 2017, Greece [27]

Healthy adults

100

52%

18–65

Mediterranean diet

Semi-quantitative FFQ: thirteen main food groups were created.

The level of adherence to the Mediterranean diet was assessed using an eleven-item composite index, the MedDietScore

Severity of epigastric pain and bloating by 5-point Likert

Zito, 2016, Italy [28]

FD/IBS/healthy control (based on ROME III)

1,134

47%

Age range 18–83 years old

Mediterranean diet

The Mediterranean Diet Quality index for children and adolescents (KIDMED): for 17 to 24 years

The Short Mediterranean Diet Questionnaire: for > 24 years

The score was classified into three levels of adherence: optimal, intermediate, low.

Presence of dyspepsia by ROME III criteria

  1. FD = Functional Dyspepsia, IBS = Irritable Bowel Syndrome, NR = Not Reported, FFQ = Food Frequency Questionnaire, GSRS = Gastrointestinal Symptom Rating Scale, OR = Odds Ratio, NS = Not Significant