Skip to main content

Table 3 Relative risks and 95% CIs for adverse pregnant outcomes with different AUC-OGTT patterns during 24–28 weeks of gestation

From: Association between the glucose pattern in oral glucose tolerance test and adverse pregnancy outcomes among non-diabetic women

Outcomes

N (%)

Relative risks (95% CI)

Crude a

P-value

Adjusted b

P-value

Preeclampsia

     

 SA pattern

98 (1.25)

Reference

 

Reference

 

 MA pattern

125 (1.58)

1.27 (0.97, 1.66)

0.078

1.17 (0.89, 1.54)

0.262

 LA pattern

157 (2.00)

1.61 (1.25, 2.08)

< 0.001

1.29 (0.99, 1.68)

0.061

Preterm birth

     

 SA pattern

321 (4.10)

Reference

 

Reference

 

 MA pattern

361 (4.57)

1.12 (0.96, 1.31)

0.143

1.10 (0.94, 1.28)

0.250

 LA pattern

406 (5.17)

1.28 (1.10, 1.48)

0.001

1.20 (1.03, 1.41)

0.020

Macrosomia

     

 SA pattern

297 (3.79)

Reference

 

Reference

 

 MA pattern

416 (5.27)

1.41 (1.21, 1.64)

< 0.001

1.34 (1.14, 1.56)

< 0.001

 LA pattern

538 (6.85)

1.87 (1.62, 2.16)

< 0.001

1.68 (1.44, 1.95)

< 0.001

Caesarean

     

 SA pattern

2,585 (33.00)

Reference

 

Reference

 

 MA pattern

2,966 (37.57)

1.22 (1.15, 1.31)

< 0.001

1.09 (1.01, 1.16)

0.018

 LA pattern

3,216 (40.97)

1.41 (1.32, 1.50)

< 0.001

1.15 (1.07, 1.23)

0.002

  1. a unadjusted; b adjusted for maternal age, preconception BMI, ethnicity, smoking history, drinking history, education, gestational weight gain, gravidity, parity, IVF, history of abortion, and history of preterm birth. The SA, MA, and LA patterns represent three distinct categories based on the AUC of OGTT, corresponding to small, medium, and large areas respectively. Relative risks and 95% CIs were calculated using the logistic regression analyses and compared against the SA pattern
  2. CI, confidence interval; AUC, area under the curve; OGTT, oral glucose tolerance test