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Table 4 Association between AUC-OGTT patterns and adverse pregnancy outcomes in different maternal age groups

From: Association between the glucose pattern in oral glucose tolerance test and adverse pregnancy outcomes among non-diabetic women

Maternal age

SA pattern

(n = 7,834)

MA pattern

(n = 7,894)

P-value

LA pattern

(n = 7,849)

P-value

< 30 years (n = 10,034)

     

 Preeclampsia

Reference

1.40 (0.95, 2.05)

0.089

1.40 (0.94, 2.08)

0.100

 Preterm birth

Reference

1.05 (0.82, 1.34)

0.699

1.07 (0.83, 1.39)

0.601

 Macrosomia

Reference

1.42 (1.13, 1.78)

0.003

1.60 (1.26, 2.01)

< 0.001

 Caesarean

Reference

1.09 (0.98, 1.22)

0.107

1.12 (1.00, 1.25)

0.059

30–34 years (n = 9,011)

     

 Preeclampsia

Reference

1.10 (0.69, 1.75)

0.697

1.18 (0.74, 1.86)

0.491

 Preterm birth

Reference

1.10 (0.85, 1.42)

0.481

1.33 (1.04, 1.71)

0.023

 Macrosomia

Reference

1.37 (1.06, 1.78)

0.016

1.75 (1.36, 2.24)

< 0.001

 Caesarean

Reference

1.08 (0.97, 1.21)

0.146

1.12 (1.01, 1.26)

0.037

≥ 35 years (n = 4,532)

     

 Preeclampsia

Reference

0.75 (0.38, 1.48)

0.748

1.37 (0.76, 2.46)

0.297

 Preterm birth

Reference

1.18 (0.83, 1.68)

0.358

1.21 (0.86, 1.70)

0.274

 Macrosomia

Reference

1.07 (0.73, 1.57)

0.748

1.81 (1.28, 2.57)

0.001

 Caesarean

Reference

1.03 (0.88, 1.21)

0.728

1.12 (0.96, 1.31)

0.153

  1. Values are reported as relative risks (95% CIs), and the relative risks were adjusted for maternal age, preconception BMI, ethnicity, smoking history, drinking history, education, gestational weight gain, gravidity, parity, IVF, history of abortion, and history of preterm birth. The SA, MA, and LA patterns represent three distinct categories based on the AUC of OGTT, corresponding to small, medium, and large areas respectively
  2. AUC, area under the curve; OGTT, oral glucose tolerance test; CI, confidence interval; BMI: body mass index; IVF, in vitro fertilization