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Table 6 Subgroup analysis for female

From: The association between HPV vaccination and new-onset cardiovascular and cerebrovascular diseases: based on a retrospective study

 

Cardiovascular diseases

Cerebrovascular diseases

Heart dysfunction

Composite outcome

Patients with outcome

HR (95% CI)

Patients with outcome

HR (95% CI)

Patients with outcome

HR (95% CI)

Patients with outcome

HR (95% CI)

HPV vaccine

Non-HPV vaccine

HPV vaccine

Non-HPV vaccine

HPV vaccine

Non-HPV vaccine

HPV vaccine

Non-HPV vaccine

Age

20–30 (n = 33,415)

1099

1229

0.904 (0.834, 0.981)

59

94

0.639 (0.461, 0.885)

115

151

0.774 (0.608, 0.987)

1143

1301

0.888 (0.82, 0.962)

30–40 (n = 10,393)

372

517

0.764 (0.668, 0.872)

39

72

0.579 (0.392, 0.855)

59

83

0.771 (0.552, 1.076)

399

569

0.743 (0.654, 0.845)

Race

Black or African American (n = 6761)

268

300

0.892 (0.757, 1.052)

22

32

0.689 (0.4, 1.186)

49

66

0.743 (0.513, 1.075)

283

322

0.877 (0.748, 1.029)

White (n = 23,141)

825

953

0.893 (0.814, 0.981)

41

83

0.511 (0.352, 0.743)

86

109

0.819 (0.617, 1.087)

857

1014

0.872 (0.796, 0.955)

Asian (n = 3428)

60

77

0.862 (0.615, 1.208)

11

10*

3.128 (0.996, 9.825)

10*

10*

0.573 (0.172, 1.903)

66

80

0.914 (0.66, 1.267)

Other race (n = 2507)

83

83

0.978 (0.722, 1.326)

10*

10*

0.494 (0.123, 1.974)

11

11

0.98 (0.425, 2.26)

86

88

0.956 (0.71, 1.287)

  1. Hazard ratio (HR) and 95% CI are provided, demonstrating outcomes among Non-HPV vaccinated individuals versus HPV vaccinated counterparts
  2. *To protect patient privacy, numbers are rounded up to 10. This may impact results, particularly for small cohorts and infrequent outcomes